PCFFGRA4 dXP' fBRL: 68\\ESBA-DC\4F_LJ-P3005X_A4SS 3dXXA4BJDM 0Rt,T`Op,T`OpRt,TT`Op,TT,TT`OpXX'  d Rt Rt@ , Rt   Canon MP600R Printer ߁ 4d A4/nBArial$"BSymbol'BWingdings$@}a~@9 Transform of plate 1 ::? ;<=>TV?@Transformed dataF`=3G3G3G3GZ[3G3G3GT3GV3GZ@9@9 #Nonlin fit of Transform of plate 1 ::;<=>3UW?@ Equation?@Table of results?@CurveFj,_b@}@?}@}@3G3G3G3GG,#WH3G?3G?3G?3G3G3Gy(s ??IY=bottom+(top-bottom)/(1+10^((logec50-x)*slope)) Y=bottom+(top-bottom)/(1+10^((logec501-x)*slope)) Y=bottom+(top-bottom)/(1+10^((logec502-x)*slope)) y=top Y=bottom P3 EC50sQI?$@??$@@?$@@@RS,BOTTOMTOPLOGEC50SLOPELOGEC501LOGEC502T03? S?}@|X.6I`IPHQHX.6(I`IPHQHX.6< I`IPHQHX.6B X.6H 8H@V W0ѥw?{vs?$k.\῔q X0NE?u?D?q ?Y<@>?/?@)V@V W0ѥw?{vs?xٿq ~?X0NE?u?q ?F?Y<?`V}?xٿV@V W0ѥw?{vs?p񿔉q fqX0NE?u?q ?5;yS?Y<@.R>.?.?<V?5V?5ʱ@.ʱ@.VA.VA.HB.HB.C.C@<e=3 Standardj3>>#J>.>.5>.>....>.;>.ǚ>....`>.}>.>....~x>.>.}>.=.)=.=...v=R=j=={==A<=hj=B-=@<O=@<e=9 Drug 19>>#J>u>>*:R>/>f>>>#?k+>N>s>....J{>.k7>.ڬ:>.j>.%$>.9>.... =.Tt=.=.......=.QZ=.I=.n4=.7<.=@<e=9 Drug 29>>#J>3>ྮ>5>?>~x> u>=Ԛf=ı=j=n=(~ =....O=.I=.i^=.{=.猨=.R=....r=.)=.0*)=....... =.B-=.%=.9E=.g<.<@<Te= zero*.>.>.#J>@<Ve=< pos control<.i^=.*=.%=@@ &Transform of plate 1:Transformed data  0 =nn$(h $n$n@s JJ@ JJ@ JJ@ (@s'@s'@s (@s'@s'@s (@s'@s'@s (U@s'@s'@s (W@s'@s'@s< f  nM@< f= Standard@< f= Drug 1@< f= Drug 2@<Uf= zero@<Wf= pos control@@ 4Nonlin fit of Transform of plate 1:Table of results  0 $(h $##$# J@ @ @ @ X@ Y@ ^@<&f* $$  $5HmppIQ`0I<IX@IJP I_PI_PIJ IQ00I<IX`@IJ  I_PI_ PI0IQ 0I< IX @IJ I_pPI_@PImpII5$Hp ICIQ00IQ0I<IJ I `/H I I I`I3 EC50sBest-fit values BOTTOM TOP LOGEC50 SLOPE LOGEC501 LOGEC502Std. Error BOTTOM TOP LOGEC50 SLOPE LOGEC501 LOGEC50295% Confidence Intervals BOTTOM TOP LOGEC50 SLOPE LOGEC501 LOGEC502Goodness of Fit Degrees of Freedom R Absolute Sum of Squares Sy.xConstraints BOTTOM TOP SLOPEData Number of X values Number of Y replicates Total number of values Number of missing values@<&f+ $$ Standard$5H.H5H.HJ IJ@ I8B<I5H5H.HJ IJ@ IBItIItIJ IJ I6C6C.H5HCCtI_0 PImpIoC;H xG<H=H0.052170.3849-0.5496-1.921(not used)(not used)0.0089230.011530.032450.3922(not used)(not used)0.03439 to 0.069960.3619 to 0.4078-0.6143 to -0.4849-2.702 to -1.139(not used)(not used)0.93720.03799BOTTOM is sharedTOP is sharedSLOPE is shared2032733@<&f- $$ Drug 1$5H.HJ I.H.HJ0 I4B<I5HJ I.H5 HJ0 IBItxIJ ItHItIJ I3C3C.`H. H?CtI_ PIm pIkC:H vG;H<H0.052170.3849(not used)-1.9210.4966(not used)0.0089230.01153(not used)0.39220.06855(not used)0.03439 to 0.069960.3619 to 0.4078(not used)-2.702 to -1.1390.3600 to 0.6332(not used)0.76670.1647BOTTOM is sharedTOP is sharedSLOPE is shared2032733@<&f. $$ Drug 2$5H.HJ I.HJ I.H4B<I5HJ I.HJ I5 HBItxIJ ItHIJ ItI3C3C.`H5 H@CtI_ PIm pIlC;H wG;H@<H0.052170.3849(not used)-1.921(not used)-1.1020.0089230.01153(not used)0.3922(not used)0.021800.03439 to 0.069960.3619 to 0.4078(not used)-2.702 to -1.139(not used)-1.145 to -1.0580.95480.01693BOTTOM is sharedTOP is sharedSLOPE is shared2032733@<X f/ $$ zero$J I.@HJ IJ IJ@ IJ I`BJ I5@HJ IJ0 IJ IJp IBJ ItIJ IJP IJ IJ I3C3C<0 I5`HBCJ I_ PIJ IcC8H rG sG9H(not used)0.3849(not used)(not used)(not used)(not used)(not used)0.01153(not used)(not used)(not used)(not used)(not used)0.3619 to 0.4078(not used)(not used)(not used)(not used)-0.019060.01431(not used)TOP is shared(not used)203357@<Y f0 $$ pos control$5HJp IJ IJ IJP IJ IdB<IJ IJ IJP IJ IJ IBIJP IJ IJ IJ0 IJ I7C7C<p IC IHCt@IJ IJ  IlC;H wG wG<H0.05217(not used)(not used)(not used)(not used)(not used)0.008923(not used)(not used)(not used)(not used)(not used)0.03439 to 0.06996(not used)(not used)(not used)(not used)(not used)-0.087480.0006351BOTTOM is shared(not used)(not used)203357@<^e,  Global (shared)J5H.H.H<0I5`H.@H@ItItPIH. H.@ H5 Hso0.052170.3849-1.9210.0089230.011530.39220.03439 to 0.069960.3619 to 0.4078-2.702 to -1.139810.88790.23460.05381@@ )Nonlin fit of Transform of plate 1:Curve  0 nnKJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJ$Jh KKv JJ@ @s @s @s Z@s [@<&f  nMЉ<@<&f(  Standard@<&f(  Drug 1@<&f(  Drug 2@<Z f(  zero@<[ f(  pos control@@ controls plate 1 : 0 $$JJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJ$J(h  u   u   JJ@  @t !@t "@t @ @< e  ST*.i^=.*=.%=@<!e  0.08 nM growth factor*.>.>.#J>@<"e  FM*.>./{>.4Q>@@ !Project info 1 list of constants  0 nnJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJJ$J(h JJR JJ@ S@<Re( R ConstantNmpI_PIQ0I5HX@I<IFBExperiment DateExperiment IDNotebook IDProjectExperimenterProtocol@<Se) R ValueJ I Mar-4-2008@@A B"4( C 4 DE X=Log(X) A@A B" PCDEA@A B" PCDEA@AB" PCDEA@AB" PCDEA@AB" PCDEA@A B" PCDEA@A"B" PCDEA@A#B" PCDEA@A%B" PCDEA@A'B" PCDEA@AKB" PCDEA@ATB" PCDEA@AVB" PCDEA@AXB" PCDEA@AYB" PCDEA@A[B" PCDEA@AnB" PCDEA@AoB" PCDEA@ApB" PCDEA@AsB" PCDEA@AtB" PCDEA@AvB" PCDEA@AwB" PCDEA@AxB" PCDEA@ Transform of plate 1 graph : 0 x2x  dz %%%%%%UWZ %[ %, ,  <ݫ@`ff @`ff <??<Y@Y@@%z`ff@33 llN{? 0l ?`ff`ff%[ %w-&pos.contros.contr%@%z@33 @xVԿq?0Z 0l?@33 %[ %w-@%@%z@ @ffffV4?Z 0l(?@@%[ %w-&@@neg.contreg.contr%@%z?O贁N;? 0l?%[ %w?O%@%zY@Z 0l$@%[ %wY@%@%zY@Z 0l$@%[ %wY@%@%zY@UUUUUU? 0l$@%[ %wY@UU%@%zY@Z 0l$@%[ %wY@%@%zY@Z 0l$@%[ %wY@%@ " # !  b g  C  !x @  o  { 0(} .?@>?/? xxdA )(@01Zx @     0(@==h@?`V}? xxdA )(@01Zx @  ' K 3 0(@==h@@